two. Histamine Receptor Antagonism: Some sedatives, like antihistamines, exert their sedative effects by blocking histamine receptors while in the Mind, specially H1 receptors. Histamine performs a role in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t blend sedatives with each other or with other drugs https://sedativesdrugs30863.affiliatblogger.com/85111786/sedative-drugs-for-pain-relief-best-options-recommendations