You will find a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to lower afferent pain transmission and develop analgesia. Hence, medicine like clonidine that goal alpha-2 receptors can influence the transmission of discomfort. Clonidine is dispersed in breast milk; https://wardf606moh8.bleepblogs.com/profile