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There exists a release of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to minimize afferent suffering transmission and create analgesia. Hence, medicines like clonidine that target alpha-2 receptors can influence the transmission of agony. For those who get dizzy when standing: https://joyces580uph6.actoblog.com/profile

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